calcium bis(2-oxopropanoate)
Calcium Pyruvate
CAS: 52009-14-0
Molecular Formula: C3H6CaO3
calcium bis(2-oxopropanoate) - Names and Identifiers
| Name | Calcium Pyruvate |
| Synonyms | CALCIUM PYRUVIC Calcim pyruvate Caclium pyruvate Calcium Pyruvate CALCIUM PYRUVATE Pyruvic acid calcium Pyruvate (Ca,Mg,Na,Etc) Pyruvic acid Calcium salt PYRUVIC ACID CALCIUM SALT calcium bis(2-oxopropanoate) propanoate, 2-oxo-, calcium salt 2-oxo-propanoic acid calcium salt |
| CAS | 52009-14-0 |
| EINECS | 257-599-9 |
| InChI | InChI=1/2C3H4O3.Ca/c2*1-2(4)3(5)6;/h2*1H3,(H,5,6);/q;;+2/p-2 |
calcium bis(2-oxopropanoate) - Physico-chemical Properties
| Molecular Formula | C3H6CaO3 |
| Molar Mass | 130.16 |
| Density | 890 at 25℃ |
| Melting Point | >245°C (dec.) |
| Boling Point | 165°C at 760 mmHg |
| Flash Point | 54.3°C |
| Solubility | Water (Sparingly, Heated) |
| Vapor Presure | 1.24hPa at 25℃ |
| Appearance | Crystalline powder |
| Color | White to Pale Yellow |
| Storage Condition | Inert atmosphere,Room Temperature |
| MDL | MFCD00037199 |
| Use | Used as raw materials for medicine and food additives |
calcium bis(2-oxopropanoate) - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
calcium bis(2-oxopropanoate) - Upstream Downstream Industry
| Raw Materials | Pyruvic acid Pyruvic acid DL-Lactic acid DL-Lactic acid |
calcium bis(2-oxopropanoate) - Reference Information
| LogP | -1.24 at 25℃ and pH7 |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| calcium salt of pyruvate | calcium pyruvate is the calcium salt of pyruvate, very stable, white crystalline powder, odorless, almost neutral, slightly soluble in water. Pyruvate is extremely unstable and easily oxidized. Weak oxidants Fe and H2O2 can oxidize pyruvate to acetic acid and release carbon dioxide. Pyruvate is an intermediate product in the process of carbohydrate metabolism in the organic body. It is also a necessary transit station for the metabolism of proteins and lipids. It is a colorless and pungent liquid under natural conditions, with a boiling point of 165 ℃ (decomposition), It is easily soluble in water. In addition to the typical properties of hydroxy acid and ketones, it also has the characteristics of a-keto acid. Pyruvate is the simplest a-keto acid (belonging to hydroxy acid). At present, calcium pyruvate can only be chemically synthesized in our country, and all the calcium pyruvate produced is industrial raw material grade. The calcium pyruvate obtained in this way is a racemate (that is, calcium pyruvate and dextrorotatory calcium pyruvate are as many), while only pyruvate with left-handed structure can be absorbed by the human body. At present, most of the acetone acid products used in medicine and weight loss in our country need to be imported from abroad. Japan's production technology in this area is in an international leading position, and it can produce L-pyruvate products through biological fermentation. Used as raw materials and food additives for medicine. As a dietary supplement, calcium pyruvate has the effects of accelerating fat consumption, reducing weight, enhancing human endurance, and improving competitive performance; it has a special protective effect on the heart, which can enhance the efficacy of heart muscles and reduce heart disease or heart ischemia. Damage caused; at the same time, calcium pyruvate has significant effects such as phagocytosis of free radicals in the body and inhibiting the generation of free radicals. Calcium pyruvate is also a calcium nutritional supplement. Although its calcium content is not 20% enough, unlike other calcium supplements, acid ions will increase the burden on the liver and kidney and have side effects. Pyruvate ions can enter cells to participate in organic matter metabolism and lose weight without affecting protein storage. |
| pyruvate | pyruvate is a component of the human body. it is mainly involved in the metabolism of sugar and fat in the human body, and is also one of the intermediate products of carbohydrate metabolism. Pyruvate and the salt it produces are widely used in the field of medicine, used in the production of sedatives, antioxidants, antiviral agents, synthetic drugs for the treatment of hypertension, etc. Pyruvic acid is also called acetoformic acid, pyrogluconic acid, 2-oxopropionic acid. Light yellow to yellow transparent liquid. It smells like acetic acid. It has a sour taste. Natural products are found in mint and sucrose fermentation broth. Relative molecular mass 88.06. Relative density 1.2271. Melting point 13.8 ℃. Boiling point 165 ℃ (decomposition), 106.5 ℃(13.332 × 103Pa), 85.3 ℃(5.333 × 103 Pa), 70.8 ℃(2.666 × 103Pa), 57.9 ℃(1.333 × 103 Pa), 45.8 ℃(0.667 × 103Pa), 21.4 ℃(0.133 × 103 Pa). Flash point 82 ℃. 1.4280 refractive index. Miscible with water, ethanol, ether, etc. The color darkens in the air. It polymerizes slowly when heated, is full of reactivity, and is easy to react with nitrides, aldehydes, halides, phosphides, etc., and participates in the biochemical synthesis and metabolism of sugar metabolism, colloids, amino acids, proteins, etc., and alcohol fermentation. When applied, it is reduced to lactic acid in the muscle, oxidized again at rest and partially converted to glycogen. Rat oral LD502100mg/kg. Uses: It is used in the synthesis of medicines, amino acids (L-tyrosine substrates), etc., which can improve efficiency, especially in the pharmaceutical industry, which can shorten the process and simplify the process, such as the 2-Phenylocynic acid made of this product is an antipyretic, analgesic, diuretic drug. Using this product as a raw material can greatly reduce production costs; in addition, it is also used as an anti-tuberculosis drug, isoniazid calcium pyruvate, hormone synthesis, the raw material of insect repellent pamote (Pyrunium pamote); it is also used as a raw material for pesticides; pyruvate, indole and ammonia are used as raw materials for biochemical reactions to produce tryptophan; the production of monosodium glutamate is to improve L-threonine This product can be used in the yield; spices are edible spices allowed in my country's GB2760-1996 regulations. preparation method: 1, using lactate as raw material for gas phase or liquid phase oxidation to obtain acetone ester, further hydrolysis can be obtained. 2, using tartaric acid as raw material, adding potassium bisulfate and sodium bisulfate, heating to 210~220 ℃, dehydrogenation, crude pyruvic acid can be obtained, and then refined by vacuum distillation. 3.2, 2-dichloropropionic acid is used as raw material, sodium hydroxide is used, pH = 6 is adjusted, and hydrolysis is carried out. |
| weight loss and fat removal | calcium pyruvate enters the body and is first replaced by hydrochloric acid secreted by the stomach into a weak organic acid-pyruvate (molecular weight 88), which is easy to penetrate The cell membrane enters the cell, reaches the energy processing plant-mitochondria of the body's cells through osmosis, and oxidizes and burns the imported fatty acids (mainly long-chain) to supply energy, the macroscopic performance of the body is fat loss and weight loss. The results of scientific experiments at the University of Pittsburgh Medical Research Center in the United States are surprising. Calcium pyruvate can increase fat consumption by at least 48%. The researchers of the institution allowed the subjects to supplement calcium pyruvate daily while taking pictures of high-fat foods. The cholesterol and low-density lipoprotein (LDL) in the plasma were reduced by 4% and 5%, respectively, while those who only ate high-fat foods The cholesterol of the subjects who did not eat calcium pyruvate remained unchanged; after receiving calcium pyruvate for six weeks, their heart rate, blood pressure, and heart rate/blood pressure were measured, and they were reduced by 9%, 6%, and 12%, respectively. Ronald Stank, MD, of the University of Pittsburgh Medical Research Center, said that it is through this participation in fat oxidation to manipulate fat metabolism. Therefore, calcium pyruvate has significant effects on weight loss and fat reduction. At present, two kinds of health foods have been available in China. |
| taking side effects | when taking calcium pyruvate, people will worry about side effects. taking a certain amount of calcium pyruvate will not cause side effects to our human body. If you take an overdose of calcium pyruvate at one time, there will be certain side effects, especially abdominal ringing, flatulence, nausea and other symptoms. |
| use | used as raw materials and food additives for medicine |
Last Update：2024-04-09 15:16:50
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Raw Materials for calcium bis(2-oxopropanoate)